Signal Transduction Reagents and Kits
Cell Biolabs Inc ViraDuctin™ Lentivirus Transduction Kit, 40 transductions
The rate at which lentiviral vectors bind to and infect cells is mostly controlled by diffusion. During lentivirus infection, only a small fraction of the lentiviral vectors can transduce target cells. Virion adsorption is the limiting step of this process. The use of polycations, such as Polybrene, is standard in many lentiviral infection protocols owing to the observations of improved infection efficiency. Its mechanism of action is thought to involve neutralization of electrostatic repulsion between virion and cell membranes, enhancing attachment. ViraDuctin™ Lentivirus Transduction Kit is a proprietary formulation for the transduction of lentivirus. After forming a complex with lentivirus in culture medium, the ViraDuctin™ reagents typically provide higher transduction efficiency in many cell types compared to reagents such as Polybrene. It is ideal for transduction of nonpermissive cells such as primary cells and stem cells. 40 transductions.
Enzo Life Sciences ML-7. HCl (10mg). CAS: 109376-83-2
Potent and selective inhibitor of MLC kinase (Ki=0.3 µM). It inhibts also smooth-muscle myosin light chain kinase, protein kinase C (PKC) and cAMP-dependent protein kinase (PKA). Alternative name: 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine . HCl. Purity: ≥99%. Solubility: Soluble in DMSO (10mg/ml), ethanol/water (1:1, 10mg/ml), 100% ethanol (warm) and methanol. Long Term Storage: -20°C.
Revvity Health Sciences Inc Terbium SureFire Ultra Human Phospho-STAT3 (Tyr705 ) Detection Kit, 10,000 Assay Points
Terbium SureFire Ultra Human Phospho-STAT3 (Tyr705 ) Detection Kit, 10,000 Assay Points
Enzo Life Sciences AMPIPROBE Ureaplasma spp. / M. genitalium / M. hominis Assay Kit (100tests)
The AMPIPROBE Ureaplasma spp. / M. genitalium / M. hominis (UMM) Assay is a real-time polymerase chain reaction (qPCR) assay for the qualitative detection of Ureaplasma spp. (Ureaplasma parvum and Ureaplasma urealyticum), Mycoplasma genitalium, and Mycoplasma hominis DNA. The kit uses the AMPIPROBE assay platform which takes advantage of paired fluorophore- and quencher-labeled primers specific for each of the target species as well as an internal control. The kit contains all reagents necessary for PCR-based detection of Ureaplasma spp., Mycoplasma genitalium, and Mycoplasma hominis DNA. A positive PCR control consisting of a mixture of the target templates and a negative PCR control that results negative for UMM, but positive for the internal control (human β-globin). Please read the complete kit insert before performing this assay. Applications: qPCR. Species reactivity: Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma spp.
Takara Bio Lenti-X™ Concentrator, 500 ml
The Lenti-X Concentrator is a complete reagent for the concentration of infectious lentiviral vector particles. This reagent provides a scalable alternative to ultracentrifugation for viral particle concentration. Vector supernatants can be concentrated 10–100 fold, depending upon the volumes used. 500ml
MilliporeSigma BIOLOGY CHEMISCREEN153 MEMB
Life Sciences,Apoptosis & Cell Biology,CHEMISCREEN™ MEMBRANE PREPARATION RECOMBINANT HUMAN u (Mu) OPIOID RECEPTOR
AdipoGen SB202190 (1 mg)
SB202190 (1 mg), Adipogen Life Sciences. Chemical. CAS: 152121-30-7. Formula: C20H14FN3O. MW: 331.3. Potent and cell permeable p38 MAP kinase inhibitor. Apoptosis inducer. Inhibits p38alpha and beta, but not gamma and delta isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. JNK activator. Autophagic vacuole inducer
CPC Scientific Glp-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro-OH (trifluoroacetate salt) 25MG
Nonapeptide capable of inhibiting the conversion of angiotensin I to angiotensin II, in vitro and in vivo. Bradykinin Potentiator.SEQUENCE: Glp-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro-OH (trifluoroacetate salt)ONE-LETTER SEQUENCE: Glp-WPRPQIPPMOLECULAR FORMULA: C53H76N14O12MOLECULAR WEIGHT: 1101.3STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [35115-60-7]SYNONYMS: RESEARCH AREA: CardiovascularREFERENCES:M.A. Ondetti et al., Biochemistry, 10, 4033 (1971)H.S. Cheung and D.W. Cushman, Biochim. Biophys. Acta, 293, 451 (1973)L.C. Martin et al., Biochem. J., 184, 713 (1979)D.I. Marlborough et al., Arch. Biochem. Biophys., 210, 43 (1981)SKU(s): ACEI-001A, ACEI-001B, ACEI-001C
Medchemexpress LLC MC-Val-Cit-PAB-vinblastine | 2055896-92-7 | 99.5% | 1366.62 | C74H97N10O15 | 10 MG
MC-Val-Cit-PAB-vinblastine is a drug-linker conjugate for antibody-drug conjugate (ADC) research that links the microtubule inhibitor vinblastine to a cleavable val-cit-PAB-type linker. It is supplied as a white to light brown solid (CAS 2055896-92-7), with molecular formula C74H97N10O15 and molecular weight 1366.62 g/mol. Intended for research and analytical applications; not for human therapeutic use.
- Drug-linker conjugate designed for ADC research
- Vinblastine payload with microtubule inhibitory activity
- Cleavable linker for lysosomal release
- High purity suitable for analytical applications
- Solid form, white to light brown appearance
- Storage recommendations: 4°C sealed; in solvent -80°C (6 months) or -20°C (1 month)
- Available as a 10 mg pack
CPC Scientific Z-Val-Leu-Leu-CHO 1MG
SEQUENCE: Z-Val-Leu-Leu-CHOONE-LETTER SEQUENCE: ZVLL-CHOMOLECULAR FORMULA: C25H39N3O5MOLECULAR WEIGHT: 461.59STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [263563-09-3]SYNONYMS: -Secretase Inhibitor IIRESEARCH AREA: Alzheimer's DiseaseREFERENCES:G. Abbenante, et al., Biochem. Biophys. Res. Commun. 268, 133 (2000)SKU(s): AMYD-113A
Enzo Life Sciences (-)-Epigallocatechin gallate (50mg). CAS: 989-51-5
Antitumor reagent. Antioxidant. Protects cells from lipid peroxidation and DNA damage induced by reactive free radicals. Inhibits inducible nitric oxide synthase (iNOS; NOS II). Chemopreventive anticancer agent. Induces apoptosis in human cancer cell lines. Inhibits MAP kinase mediated signalling pathways. Inhibits angiogenesis. Inhibits telomerase and DNA methyltransferase. Anti-inflammatory agent. Alternative name: EGCG, (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate). Formula: C22H18O11. MW: 458.4. MI: 14: 3526. Purity: ≥98% (HPLC). Solubility: Soluble in 100% ethanol, dimethyl formamide or DMSO; slightly soluble in water. Use/Stability: Stock solutions in DMSO are stable for up to 3 months when stored at -20°C. Long Term Storage: +4°C. Handling: Protect from light. Keep under inert gas. After reconstitution, prepare aliquots and store at -20°C.
Abcam Ascorbic Acid Assay Kit
Ascorbic Acid Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Enzo Life Sciences MMP-1 Colorimetric Assay Buffer (20ml)
Formulation: Liquid. In 50 mM HEPES, 10 mM calcium chloride, 0.05% Brij-35, 1 mM DTNB, pH 7.5. Long Term Storage: -20°C.
Medchemexpress LLC HY-P1002 1mg Medchemexpress, Suc-Leu-Leu-Val-Tyr-AMC CAS:94367-21-2 Purity:>98%
Medchemexpress, HY-P1002 1mg Suc-Leu-Leu-Val-Tyr-AMC CAS:94367-21-2 Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic substrate. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Paclitaxel 10mM/1mL 33069-62-4 NSC 125973, PTX, Taxol, Onxal
Paclitaxel (NSC 125973, PTX, Taxol, Onxal) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.